After some decades, Kirigakure was manipulated by Madara Uchiha and sealed Isobu within Rin Nohara as a way to create havoc in Konoha. He was sold, together with Saiken, to Kirgakure during the Five Kage Summit by Hashirama Senju to create peace and balance among the villages.
The Three-Tails was last sealed inside Yagura Karatachi of Kirigakure.